Publications
Selected Publications
Falcone, D.J., Khan, K.M.F., Layne, T. and Fernandes, L. (1998) Macrophage formation of angiostatin during inflammation: A byproduct of the activation of plasminogen. J. Biol. Chem 273: 31480-31485.
Khan, K.M.F. and Falcone, D.J. (2000) Selective Activation of MAPKerk1/2 by Laminin-1 Peptide alpha1:Ser2091-Arg2108 Regulates Macrophage Degradative Phenotype. J. Biol. Chem. 275:4492-4498
Falcone, D.J., Borth, W., Khan, K.M.F. and Hajjar, K.A. (2001) Plasminogen-Mediated Matrix Invasion and Degradation by Macrophages is Dependent on Surface Expression of Annexin II. Blood 97:777-784.
Khan, K.M. F., Falcone, D.J. and Kraemer, R. (2002) Nerve Growth Factor Activation of Erk-1 and Erk-2 Induces Matrix Metalloproteinase Expression in Vascular Smooth Muscle Cells. J. Biol. Chem. 277:2353-2359
Khan, K.M. F., Laurie, G.W. and Falcone, D.J. (2002) Exposure of cryptic domains in the alpha1-chain of laminin-1 by elastase stimulates macrophages urokinase and MMP-9 expression. J. Biol. Chem. 277:13778-13786.
Borer, J.S., Truter, S., Herrold, E.H., Falcone, D.J., Pena, M., Dumlao, T.F., Lee, J.A., Supino, P.G. (2002) Myocardial fibrosis in chronic aortic regurgitation: molecular and cellular responses to volume overload. Circulation 105:1837-1842.
Brownstein, C., Deora, A.B., Jacovina, A.T., Weintraub, R., Gertler, M., K.M.F. Khan, Falcone, D.J. and Hajjar, K.A. (2004) Annexin II mediates plasminogen-dependent matrix invasion by human monocytes: Enhanced expression by macrophages. Blood 103:317-324
Khan, K.M.F., Howe, L.R., and Falcone, D.J. Extracellular matrix induced cyclooxygenase-2 regulates macrophage proteinase expression (2004) J. Biol. Chem. 279:22039-22046
Pavlovic, S., Du, B., Sakamoto, K., Khan, K.M.F., Natarajan, C., Breyer, R.M., Dannenberg, A.J. and Falcone, D.J. (2006) Targeting PGE2 Receptors as an Alternative Strategy to Block COX-2-dependent Extracellular Matrix-induced MMP-9 Expression by Macrophages. J. Biol. Chem. 281:3321-3328.
Du, B., Leung, H., Khan, K.M.F., Miller, C.G., Subbaramaiah, K., Falcone, D.J., Dannenberg, A.J. (2007) Tobacco Smoke Induces Urokinase-type Plasminogen Activator and Cell Invasiveness: Evidence for an EGFR-dependent Mechanism. Cancer Res. 67:8966-72.
